Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length238 amino acids

Chemical FormulaC1195H1829N321O369S4

DescriptionStandard

        MVWNSEHNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIKSIDQATILVTPIPDCKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDPRDQAGTASGNGSQIETGQKWLDLSVTNNGEGAKIPSNIADKLRGRHYDSFRKSREDLWLEISKDPELSKQFSNDNIEAMQEGKAPTAPFAGHYVGPKQVIKKFEIHHIKPIEEGGGVYDIDNLRITMPKLHKFIHYGE
    

Molecular Weight26724.50 Da

Isoelectric Point (pI)5.20

Net Charge (pH 7.0)-11.67

Net Charge (pH 7.4) -12.44

Charge Density (pH 7.0) -0.0490

GRAVY Index-0.72

Hydrophobic Moment 0.64

Boman Index-0.05

Instability Index49.92

Aliphatic Index 71.72

Aromaticity 0.0882

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042606 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)