Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC82H111N21O22

DescriptionStandard

        DLPNYNWNSFGLRF
    

Molecular Weight1742.89 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0171

GRAVY Index-0.74

Hydrophobic Moment 0.31

Boman Index0.02

Instability Index38.21

Aliphatic Index 55.71

Aromaticity 0.2857

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 717.55

LogP -5.56

H-bond Donors 24.0

H-bond Acceptors 22.0

Rotatable Bonds 51.0

Heavy Atoms 125.0

Ring Count 6.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0432407 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyKISS1

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide KISS1R agonist KISS1R agonist

Targethuman KISS1 receptor (GPR54)

Activity7.22±0.07 nM

MethodEC50 (aequorin-based functional assay)

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