‹ ›
MYP_020075
← PREVIOUS NEXT → BACK
Basic Information
Temporin-1RNb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C73H121N17O13
Standard
Sequence
FLPLKKLRFGLL
Physicochemical Analysis
1444.85 Da
11.17
2.76
2.55
0.2298
0.86
0.22
0.23
27.12
162.50
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
488.57
1.11
17.0
16.0
48.0
103.0
3.0
11.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0159910 VERIFIED: YES
Provenance & Taxonomy
Rana nigromaculata [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus cereus
3.13 μM
MIC
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
RECORD: Rec_0175458 VERIFIED: YES
Provenance & Taxonomy
Rana nigromaculata [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human breast adenocarcinoma MCF-7
11.4
IC50
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
RECORD: Rec_0175642 VERIFIED: YES
Provenance & Taxonomy
Rana nigromaculata [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
136.3±5.6 μM
HC50
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
RECORD: Rec_0176730 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
RECORD: Rec_0235434 VERIFIED: YES
Provenance & Taxonomy
Rana nigromaculata [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
cancer cells MCF 7 cells and Hela cells
~12 μM
IC50
PaperPurification, molecular cloning, and antimicrobial activity of peptides from the skin secretion of the black-spotted frog, Rana nigromaculata.
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 3 of 5