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MYP_020075
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Basic Information
Temporin-1RNb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C73H121N17O13
Standard
Sequence
FLPLKKLRFGLL
Physicochemical Analysis
1444.85 Da
11.17
2.76
2.55
0.2298
0.86
0.22
0.23
27.12
162.50
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
488.57
1.11
17.0
16.0
48.0
103.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013486 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
Temporin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
RECORD: Rec_0014353 VERIFIED: YES
Provenance & Taxonomy
Rana nigromaculata [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human cervical carcinoma HeLa
12.8
IC50
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
RECORD: Rec_0027473 VERIFIED: YES
Provenance & Taxonomy
Rana nigromaculata [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Lactococcus lactis
3.13 μM
MIC
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
RECORD: Rec_0039799 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0086368 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23632907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23632907/
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