Peptide Database

Peptide NameSLAY-screened peptide P1094

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC115H161N25O31S2

DescriptionStandard

        PCTYFDSLTRWFMLDAYPNL
    

Molecular Weight2453.79 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-1.05

Net Charge (pH 7.4) -1.13

Charge Density (pH 7.0) -0.0526

GRAVY Index-0.04

Hydrophobic Moment 0.60

Boman Index0.16

Instability Index72.64

Aliphatic Index 63.50

Aromaticity 0.2500

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 889.97

LogP -4.67

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 71.0

Heavy Atoms 173.0

Ring Count 8.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351353 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/