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MYP_019980
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Basic Information
Meucin-25 (BeL-170; Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
25 amino acids
C145H240N36O34S2
Standard
Sequence
VKLIQIRIWIQYVTVLQMFSMKTKQ
Physicochemical Analysis
3095.81 Da
10.46
3.73
3.51
0.1492
0.41
0.51
0.15
21.14
128.40
0.1200
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1170.75
-4.83
41.0
40.0
107.0
217.0
4.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027628 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimalarial
mouse erythrocytes even at 101 μM
PaperPubMed PMID: 20097251 PMID20097251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20097251/
RECORD: Rec_0031849 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiparasitic
rodent malaria P. berghei
PaperCharacterization of two linear cationic antimalarial peptides in the scorpion Mesobuthus eupeus
RECORD: Rec_0164253 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Meucin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium berghei ANKA 2.34
10-20 μM
Percent inhibition; Microscopy (Giemsa staining)
PMID20097251 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20097251/
RECORD: Rec_0183302 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20097251;35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20097251/
RECORD: Rec_0219204 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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