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MYP_019911
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Basic Information
Lavracin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C108H171N27O25
Standard
Sequence
WDPYFAGVKKLTKAILAVRA
Physicochemical Analysis
2247.68 Da
10.00
2.76
2.55
0.1379
0.29
0.59
0.15
13.45
107.50
0.1500
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
840.94
-3.30
30.0
28.0
71.0
160.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009365 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
D-amino-acid content reported
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus SH1000-GFP strain
50 μM
MIC
PaperRational Design of Membrane-Pore-Forming Peptides
RECORD: Rec_0116127 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MEC-7
50-100 μM
EC50
PaperPubMed PMID: 28799716 PMID28799716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28799716/
RECORD: Rec_0179518 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
μM
100 μM
Cytotoxicity
PaperPubMed PMID: 28799716 PMID28799716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28799716/
RECORD: Rec_0197797 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MEC-7 (Not active up to 100 μM)
PaperPubMed PMID: 28799716 PMID28799716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28799716/
RECORD: Rec_0219886 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 28799716 PMID28799716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28799716/
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