Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length132 amino acids

Chemical FormulaC663H1061N173O181S6

DescriptionStandard

        MVNFNGKHSKILAAFGMVFLSILVMFGTIGSPVKYNQNEFSNSDIQTLEKSSLEVNLAKIINKYSKKTTWNQAQKKASKIVNMVMTGSDVASAISIVLGAFSFGTVTAIAWAARMSLKWYIKRKGKKAAVTW
    

Molecular Weight14543.96 Da

Isoelectric Point (pI)10.23

Net Charge (pH 7.0)12.58

Net Charge (pH 7.4) 12.28

Charge Density (pH 7.0) 0.0953

GRAVY Index0.12

Hydrophobic Moment 0.69

Boman Index0.13

Instability Index10.05

Aliphatic Index 90.91

Aromaticity 0.1061

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5751.01

LogP -53.23

H-bond Donors 202.0

H-bond Acceptors 201.0

Rotatable Bonds 496.0

Heavy Atoms 1023.0

Ring Count 20.0

Amide Bonds 144.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327411 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus pumilus [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal