Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC354H579N101O87S7

DescriptionStandard

        MKLLLLTLAALLLLSQLTPGGTQKCWNLHGRCRQKCSKRERVYVYCTNNKLCCVKPKFQPREKLWPF
    

Molecular Weight7866.46 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1571

GRAVY Index-0.25

Hydrophobic Moment 0.43

Boman Index-0.09

Instability Index29.33

Aliphatic Index 91.64

Aromaticity 0.0896

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3064.75

LogP -23.68

H-bond Donors 113.0

H-bond Acceptors 106.0

Rotatable Bonds 263.0

Heavy Atoms 549.0

Ring Count 13.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186720 VERIFIED: NO

Provenance & Taxonomy

OrganismEnhydra lutris kenyoni [Bacterium]

FamilyDefensin

Tax ID391180

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence