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MYP_019859
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Basic Information
Peptide 130
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
3 amino acids
C23H36N10O4
Standard
Sequence
WRR
Physicochemical Analysis
516.60 Da
12.00
1.76
1.56
0.5867
-3.30
1.32
-1.42
197.60
0.00
0.3333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
261.11
-1.38
11.0
6.0
15.0
37.0
2.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043330 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
400 μM
MIC
PMID34021253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34021253/
RECORD: Rec_0117124 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
horse RBCs
Hemolysis
PMID34021253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34021253/
RECORD: Rec_0215618 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
human dipeptidyl peptidase IV
570.0
IC50
PaperLan V. T. T., Ito K., Ito S., Kawarasaki Y.. Trp-Arg-Xaa tripeptides act as uncompetitive-type inhibitors of human dipeptidyl peptidase IV. Peptides, 54, 166-170. PMID24512990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24512990/
RECORD: Rec_0279754 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
400 μM
MIC
PMID34021253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34021253/
RECORD: Rec_0362141 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
400 μM
MIC
PMID34021253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34021253/