Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC330H530N88O91S8

DescriptionStandard

        MRTFLFLFAVLFFLTPAKNAFFDEKCDKLRGTCKKNCGKNEELTSLCQKSLKCCRIIQPCGNITD
    

Molecular Weight7442.79 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.0683

GRAVY Index-0.06

Hydrophobic Moment 0.61

Boman Index-0.03

Instability Index24.20

Aliphatic Index 75.08

Aromaticity 0.1077

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2925.95

LogP -26.72

H-bond Donors 107.0

H-bond Acceptors 104.0

Rotatable Bonds 254.0

Heavy Atoms 517.0

Ring Count 9.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0202739 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus bieti [Animal]

FamilyDefensin

Tax ID61621

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0205046 VERIFIED: NO