Peptide Database

Peptide Name(D-Thr6, D-Trp8,9)galanin(1-15)ol

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC84H115N21O19

DescriptionStandard

        GWTLNTAWWLLGPHA
    

Molecular Weight1722.94 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0102

GRAVY Index0.12

Hydrophobic Moment 0.20

Boman Index0.44

Instability Index10.11

Aliphatic Index 91.33

Aromaticity 0.2000

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 621.53

LogP -2.09

H-bond Donors 22.0

H-bond Acceptors 20.0

Rotatable Bonds 46.0

Heavy Atoms 124.0

Ring Count 8.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356314 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor agonist Neuropeptide activity Signaling peptide

TargetGAL2 receptor (Rat); GAL3 receptor (Rat)

Activity>1250 nM

MethodKi