Peptide Database

Peptide NameEppin (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)

Function Ontology

Antimicrobial

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length134 amino acids

Chemical FormulaC669H1048N196O195S16

DescriptionStandard

        MKLSGFVSILVLFGLLARVQGPSLADLLFPRRCPRFREECEHQERDLCTRDRDCPKKEKCCVFNCGKKCLNPQQDICSLPKDSGYCMAYFRRWWFNKENSTCQVFIYGGCQGNNNNFQSQSICQNACEKKSSLT
    

Molecular Weight15469.71 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)6.46

Net Charge (pH 7.4) 5.96

Charge Density (pH 7.0) 0.0482

GRAVY Index-0.51

Hydrophobic Moment 0.55

Boman Index-0.14

Instability Index56.48

Aliphatic Index 60.37

Aromaticity 0.1045

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 16345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6404.54

LogP -69.81

H-bond Donors 233.0

H-bond Acceptors 219.0

Rotatable Bonds 519.0

Heavy Atoms 1076.0

Ring Count 23.0

Amide Bonds 151.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0246304 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Protease inhibitor Serine protease inhibitor Enzyme inhibitory Non-hemolytic