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MYP_019774
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Basic Information
Myxinidin (S12)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C61H98N16O16
Standard
Sequence
GIHDILKYGKPA
Physicochemical Analysis
1311.53 Da
8.51
0.85
0.59
0.0704
-0.30
0.58
0.12
16.97
105.83
0.0833
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
512.88
-2.69
17.0
18.0
42.0
93.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009521 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
MIC
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0014577 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
50 μM
MIC
PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0037900 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
MIC
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0053373 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
MIC
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0074562 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
MIC
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
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