MYP_019747
hACE2(21-55)F32K-A36E
Standard
35 amino acids
C187H277N47O64
Standard
IEEQAKTFLDKKNHEEEDLFYQSSLASWNYNTNIT
4207.48 Da
4.49
-4.14
-4.41
-0.1183
-1.11
0.52
-0.14
99.05
61.43
0.1429
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1856.73
-18.96
62.0
61.0
142.0
298.0
7.0
40.0
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0053887
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
ACE2-derived
32630
Structure & Mods
lactam-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Ⓚ (12) and Ⓔ (16) are corss-linked by lactam stapling
Bio-Activity Profile
SARS-CoV-2 spike protein-hACE2 complex
28.4 μM
IC50
RECORD: Rec_0226561
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Stapled ACE2-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Severe acute respiratory syndrome coronavirus 2
28.4 μM
IC50
RECORD: Rec_0262697
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Stapled ACE2-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Severe acute respiratory syndrome coronavirus 2
100 μM
IC50