Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC728H1136N212O205S5

DescriptionStandard

        MPKVQFKERTATDYLVVHCAATKASMDIGVREIRQWHVQKGWLDIGYHFVIRRNGTVEDGRPHNVIGAHVEGFNSRSLGICLAGGIDDKGNPQNNFTPEQFNSLKLLLTAQKRTYPQAKIVGHHDLFAGKACPSFKVSDWLQSVGL
    

Molecular Weight16298.43 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.09

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.0349

GRAVY Index-0.35

Hydrophobic Moment 0.68

Boman Index0.00

Instability Index38.11

Aliphatic Index 81.44

Aromaticity 0.0890

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6708.77

LogP -66.33

H-bond Donors 233.0

H-bond Acceptors 222.0

Rotatable Bonds 539.0

Heavy Atoms 1150.0

Ring Count 29.0

Amide Bonds 160.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0391528 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas phage PPPL-1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic