Peptide Database

Peptide NameCorazonin precursor-related peptide

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC163H245N45O55

DescriptionStandard

        SFNAASPLLANGHLHRASELGLTDLYDLQDWSSD
    

Molecular Weight3714.96 Da

Isoelectric Point (pI)4.49

Net Charge (pH 7.0)-4.36

Net Charge (pH 7.4) -4.67

Charge Density (pH 7.0) -0.1281

GRAVY Index-0.34

Hydrophobic Moment 0.41

Boman Index0.07

Instability Index51.76

Aliphatic Index 92.06

Aromaticity 0.0882

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1607.26

LogP -18.20

H-bond Donors 55.0

H-bond Acceptors 53.0

Rotatable Bonds 118.0

Heavy Atoms 263.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051893 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyCorazonin precursor-related peptide

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation ACE inhibitory

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0131244 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0222527 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyCorazonin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone