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MYP_019712
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Basic Information
Temporin-PEa (Temporin-PE peptide derivative)
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C73H120N14O16
Standard
Sequence
FLYIVAKLLSGLL
Physicochemical Analysis
1449.82 Da
8.59
0.76
0.55
0.0583
1.99
0.43
0.66
-3.83
210.00
0.1538
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
479.00
1.11
17.0
17.0
47.0
103.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0159313 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Fungus: Candida albicans
2 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0195489 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antitumor Anti-Gram-positive Anti-Gram-negative
Escherichia coli
512 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0221736 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Hemolytic
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0225269 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Cancer cell lines: NCI-H157
3.398 μM
IC50
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0270246 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Enterococcus faecalis
2 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
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