Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC409H648N106O110S8

DescriptionStandard

        MPVTKSYFMTVVVVLILVDETTGGLFGFRSSKRQEPWIACELYQGLCRNACQKYEIQYLSCPKTRKCCLKYPRKITSF
    

Molecular Weight9066.68 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)6.44

Net Charge (pH 7.4) 6.11

Charge Density (pH 7.0) 0.0826

GRAVY Index-0.06

Hydrophobic Moment 0.64

Boman Index0.01

Instability Index56.85

Aliphatic Index 79.87

Aromaticity 0.1282

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3501.92

LogP -28.38

H-bond Donors 130.0

H-bond Acceptors 125.0

Rotatable Bonds 298.0

Heavy Atoms 633.0

Ring Count 15.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117487 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0126684 VERIFIED: NO