Peptide Database

Peptide NameNeutrophil beta-defensin 8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC305H504N98O73S7

DescriptionStandard

        MRLHHLLLALLFLVLSAGSGFTQGVRNFVTCRINRGFCVPIRCPGHRRQIGTCLGPQIKCCR
    

Molecular Weight6936.33 Da

Isoelectric Point (pI)11.20

Net Charge (pH 7.0)8.70

Net Charge (pH 7.4) 8.24

Charge Density (pH 7.0) 0.1403

GRAVY Index0.36

Hydrophobic Moment 0.76

Boman Index0.06

Instability Index25.05

Aliphatic Index 103.71

Aromaticity 0.0645

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2735.91

LogP -25.72

H-bond Donors 104.0

H-bond Acceptors 92.0

Rotatable Bonds 227.0

Heavy Atoms 483.0

Ring Count 10.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096609 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function