Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length198 amino acids

Chemical FormulaC1024H1534N226O301S8

DescriptionStandard

        IDELAEVDYSLNTLPAVFQRFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEAKSGKLFYLFFFFLQTCSYFNISTEVFGSIIPEVSKYSVTPYPVMLKLMATEIPTISLEQDSFTVEIQGSMEVFAVLPDATTQSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight22082.99 Da

Isoelectric Point (pI)4.11

Net Charge (pH 7.0)-12.24

Net Charge (pH 7.4) -12.52

Charge Density (pH 7.0) -0.0618

GRAVY Index0.33

Hydrophobic Moment 0.60

Boman Index0.26

Instability Index41.53

Aliphatic Index 91.67

Aromaticity 0.1566

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8345.27

LogP -94.88

H-bond Donors 284.0

H-bond Acceptors 297.0

Rotatable Bonds 702.0

Heavy Atoms 1559.0

Ring Count 42.0

Amide Bonds 213.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058834 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaeniceps rex [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria