Peptide Database

Peptide NameNeuropeptide S precursor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC338H551N93O92S3

DescriptionStandard

        YPVPSSKVSGKSDYFLILLNSCPTRLDRSKELAFLKPILEKMFVKRSFRNGVGTGMKKTSFQRAKS
    

Molecular Weight7485.75 Da

Isoelectric Point (pI)10.41

Net Charge (pH 7.0)9.75

Net Charge (pH 7.4) 9.51

Charge Density (pH 7.0) 0.1477

GRAVY Index-0.39

Hydrophobic Moment 0.64

Boman Index-0.11

Instability Index49.43

Aliphatic Index 73.79

Aromaticity 0.1061

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3025.03

LogP -29.67

H-bond Donors 109.0

H-bond Acceptors 105.0

Rotatable Bonds 255.0

Heavy Atoms 526.0

Ring Count 11.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073538 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNeuropeptide S precursor

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Receptor modulation Immunomodulatory ACE inhibitory Sleep regulation Wake regulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min