Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1161H1767N261O343S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLQQDSFTVEIRGSMEVFAVLPDSTTQLLFTMNLAANTSIALNIFDQKLMGSLCLNRLQFSLAHSSVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25125.51 Da

Isoelectric Point (pI)4.12

Net Charge (pH 7.0)-14.15

Net Charge (pH 7.4) -14.48

Charge Density (pH 7.0) -0.0620

GRAVY Index0.39

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index46.66

Aliphatic Index 101.84

Aromaticity 0.1316

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383223 VERIFIED: NO

Provenance & Taxonomy

OrganismFregata magnificens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria