Peptide Database

Peptide NameCorticostatin 1 (Antiadrenocorticotropin peptide I) (Corticostatin I) (CS-I) (Microbicidal peptide NP-3A) (Neutrophil antibiotic peptide NP-3A)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC442H724N136O136S7

DescriptionStandard

        MRTLILLAAILLAALQAQAELFSVNVDEVLDQQQPGSDQDLVIHLTGEESSALQVPDTKGICACRRRFCPNSERFSGYCRVNGARYVRCCSRR
    

Molecular Weight10343.76 Da

Isoelectric Point (pI)7.59

Net Charge (pH 7.0)0.54

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0059

GRAVY Index-0.09

Hydrophobic Moment 0.77

Boman Index-0.06

Instability Index56.32

Aliphatic Index 94.41

Aromaticity 0.0538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4434.51

LogP -49.91

H-bond Donors 161.0

H-bond Acceptors 145.0

Rotatable Bonds 346.0

Heavy Atoms 721.0

Ring Count 9.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237879 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9986

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic