Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length286 amino acids

Chemical FormulaC1432H2233N365O401S9

DescriptionStandard

        QVCDSVAKSVHNELQTYVQTLPVTARIDAMTGIDYSLVAPPTATAQSLDAGLKGEFYSLAQRSTIPFSPLPLAFPLDHDHMVYFGASSYFFNTAGFAYHTAGALVFEITDAMIPKDVGFSLNTSVFSAFIPQLEQMYPDMPMKFKLFTPTAPFLNIGPGGISLKPVVDVQAYAILPNSSLAPLFLLSLVRNVSAVIDVRSGRIVGSLDVGRIRFSLKDSAVGTFQVRMLQSLMNTLASSILLPRLNARLDEGFPLPLPDRIQLSNILVRFHQNFLLLGADVHFQPQ
    

Molecular Weight31266.84 Da

Isoelectric Point (pI)6.31

Net Charge (pH 7.0)-1.71

Net Charge (pH 7.4) -2.27

Charge Density (pH 7.0) -0.0060

GRAVY Index0.30

Hydrophobic Moment 0.67

Boman Index0.20

Instability Index38.75

Aliphatic Index 102.97

Aromaticity 0.1014

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 11920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395453 VERIFIED: NO

Provenance & Taxonomy

OrganismAtrichornis clamosus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria