Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1155H1779N265O350S9

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFRPFIDLDLKGVVFPAGNYTDSLYVPASFTILDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPVISLEQDSFTVQIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEIIPSANAKLSKGFPLP
    

Molecular Weight25265.63 Da

Isoelectric Point (pI)4.08

Net Charge (pH 7.0)-15.14

Net Charge (pH 7.4) -15.48

Charge Density (pH 7.0) -0.0661

GRAVY Index0.36

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index47.29

Aliphatic Index 103.49

Aromaticity 0.1179

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319844 VERIFIED: NO

Provenance & Taxonomy

OrganismEulacestoma nigropectus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria