Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length303 amino acids

Chemical FormulaC1539H2451N363O436S15

DescriptionStandard

        LLAWLTTESLEIMFFFLLMQICPLVNKAVEDLNTELKTLNVLAKVDKYAEIEYSMVSSPEVSKSSIDLSLKGEFYNIGKHQEPPFSPTAISLPPQTDKMLYIALSAFTPNSAGFVYNKAGVLSLYITDDMVPKASPFRLNTKTFGVFIPQIAKQFPGLMMKLLLKTEESPKVSFEPKNATLQTSATMTAYAIQPNGTLSPLFVLNVESSVTAHLFLSGMNIAGSLSLNKMKLTLGTSYVGQFQVGTLDTIFQMVLKMVVIPIVNAQLEKGYPLPALKKMQLINPQLQILKDYMLIGTDVQFIS
    

Molecular Weight33496.07 Da

Isoelectric Point (pI)7.89

Net Charge (pH 7.0)0.94

Net Charge (pH 7.4) 0.54

Charge Density (pH 7.0) 0.0031

GRAVY Index0.25

Hydrophobic Moment 0.59

Boman Index0.20

Instability Index45.66

Aliphatic Index 104.88

Aromaticity 0.0924

Extinction Coeff. Reduced 20400.00

Extinction Coeff. Oxidized 20400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377666 VERIFIED: NO

Provenance & Taxonomy

OrganismKryptolebias marmoratus [Bacterium]

FamilyBPI

Tax ID37003

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence