Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC293H470N88O74S8

DescriptionStandard

        MRLHHLLLELLFVVLSAGSGISDFASCHTNGGICLPNRCPGHMIQIGICFRPRVKCCRSW
    

Molecular Weight6665.93 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)3.79

Net Charge (pH 7.4) 3.28

Charge Density (pH 7.0) 0.0632

GRAVY Index0.45

Hydrophobic Moment 0.49

Boman Index0.16

Instability Index28.16

Aliphatic Index 102.33

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2545.13

LogP -22.54

H-bond Donors 96.0

H-bond Acceptors 90.0

Rotatable Bonds 215.0

Heavy Atoms 463.0

Ring Count 12.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0200563 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal