Peptide Database

Peptide NameSomatostatin-28

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC145H219N41O40S2

DescriptionStandard

        SIEPPNNLPPRERKAGCKNFYWKGFTSC
    

Molecular Weight3240.67 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0872

GRAVY Index-1.04

Hydrophobic Moment 0.40

Boman Index-0.19

Instability Index61.34

Aliphatic Index 31.43

Aromaticity 0.1429

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1316.30

LogP -13.46

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 100.0

Heavy Atoms 228.0

Ring Count 9.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111302 VERIFIED: NO

Provenance & Taxonomy

OrganismPlatichthys flesus [Animal]

FamilySomatostatin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide17-28

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0162040 VERIFIED: YES

Provenance & Taxonomy

OrganismPlatichthys flesus [Animal]

Familysomatostatin

Tax ID8260

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide17-28

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour