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MYP_019373
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Basic Information
Signiferin-2.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
15 amino acids
C72H128N18O17S
Standard
Sequence
IIGHLIKTALGMLGL
Physicochemical Analysis
1549.96 Da
8.76
0.85
0.59
0.0564
1.56
0.44
0.61
3.67
188.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
545.65
-1.35
19.0
20.0
53.0
108.0
1.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0267744 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus epidermidis
25 μM
MIC
PMID18601958;16470724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18601958/
RECORD: Rec_0279718 VERIFIED: YES
Provenance & Taxonomy
Crinia signiferin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Micrococcus luteus ATCC 9341
25 μM
IC50
PaperHost-defence skin peptides of the Australian Streambank Froglet Crinia riparia: isolation and sequence determination by positive and negative ion electrospray mass spectrometry.
RECORD: Rec_0281409 VERIFIED: YES
Provenance & Taxonomy
Crinia signiferin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Streptococcus uberis
25 μM
IC50
PaperHost-defence skin peptides of the Australian Streambank Froglet Crinia riparia: isolation and sequence determination by positive and negative ion electrospray mass spectrometry.
RECORD: Rec_0336941 VERIFIED: YES
Provenance & Taxonomy
Crinia signiferin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis ATCC 14990
25 μM
IC50
PaperHost-defence skin peptides of the Australian Streambank Froglet Crinia riparia: isolation and sequence determination by positive and negative ion electrospray mass spectrometry.
RECORD: Rec_0338900 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
25 μM
MIC
PMID18601958;16470724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18601958/
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