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MYP_019373
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Basic Information
Signiferin-2.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
15 amino acids
C72H128N18O17S
Standard
Sequence
IIGHLIKTALGMLGL
Physicochemical Analysis
1549.96 Da
8.76
0.85
0.59
0.0564
1.56
0.44
0.61
3.67
188.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
545.65
-1.35
19.0
20.0
53.0
108.0
1.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045714 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Leuconostoc lactis
12 μM
MIC
PMID15317042;16470724;18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15317042/
RECORD: Rec_0058168 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus epidermidis ATCC14990
25 μM
MIC
PMID15317042;16470724;18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15317042/
RECORD: Rec_0066903 VERIFIED: YES
Provenance & Taxonomy
Crinia signiferin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterobacter cloacae ATCC 13047
>100 μM
IC50
PaperHost-defence skin peptides of the Australian Streambank Froglet Crinia riparia: isolation and sequence determination by positive and negative ion electrospray mass spectrometry.
RECORD: Rec_0089207 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus ATCC 9341
25 μM
MIC
PMID15317042;16470724;18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15317042/
RECORD: Rec_0110295 VERIFIED: NO
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Enzyme inhibitory
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