Peptide Database

Peptide NameMaximins 2 H8 type 1 [Cleaved into: Maximin-2; Maximin-H8]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC704H1159N197O222S4

DescriptionStandard

        MNFKYIVAVSFLIASAYARSEENEIQSLSQRDVLEEESLREMRGIGTKILGGVKTALKGALKELASTYVNGKRTAEEHEVMKRLETVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKRILGPVLGLVSNALGGLLKNIG
    

Molecular Weight16063.18 Da

Isoelectric Point (pI)5.61

Net Charge (pH 7.0)-2.37

Net Charge (pH 7.4) -2.69

Charge Density (pH 7.0) -0.0165

GRAVY Index-0.36

Hydrophobic Moment 0.71

Boman Index-0.06

Instability Index48.43

Aliphatic Index 96.18

Aromaticity 0.0556

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6854.57

LogP -67.73

H-bond Donors 239.0

H-bond Acceptors 225.0

Rotatable Bonds 565.0

Heavy Atoms 1127.0

Ring Count 11.0

Amide Bonds 153.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154276 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin; Maximin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Cytolytic Hemolytic

TargetNo Target Organism Found

RECORD: Rec_0413768 VERIFIED: NO