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MYP_019297
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Basic Information
HC-toxin
Antimicrobial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Toxoplasma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
AAAXEX
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027694 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic tetrapeptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Aoe=2-amino-9,10-epoxi-8-oxodecanoic acid
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-Toxoplasma
Toxoplasma gondii
0.015 μg/mL
MIC; [3H] Uracil incorporation assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0053448 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic tetrapeptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Aoe=2-amino-9,10-epoxi-8-oxodecanoic acid
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-Cryptosporidium
Cryptosporidium parvum
0.18 μg/mL
MIC; ELISA based assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0244615 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic tetrapeptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Aoe=2-amino-9,10-epoxi-8-oxodecanoic acid
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum
0.031 μg/mL
MIC
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0257067 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic tetrapeptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Aoe=2-amino-9,10-epoxi-8-oxodecanoic acid
Bio-Activity Profile
Antimicrobial Antiparasitic Anticoccidial
Eimeria tenella
0.016 μg/mL
MIC; [3H] Uracil incorporation assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0358039 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic tetrapeptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Aoe=2-amino-9,10-epoxi-8-oxodecanoic acid
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-Neospora
Neospora caninum
0.015 μg/mL
MIC; [3H] Uracil incorporation assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
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