Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC353H566N100O90S8

DescriptionStandard

        IPAAMRIFFLIFAAFILLAQIFPARGALQRQLHCNKMSGRCEAECLDFEEKIGGCRAELTPFCCKKARKN
    

Molecular Weight7907.41 Da

Isoelectric Point (pI)9.12

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.0685

GRAVY Index0.20

Hydrophobic Moment 0.45

Boman Index0.05

Instability Index54.58

Aliphatic Index 86.71

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3054.74

LogP -23.61

H-bond Donors 111.0

H-bond Acceptors 104.0

Rotatable Bonds 266.0

Heavy Atoms 551.0

Ring Count 11.0

Amide Bonds 74.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0327685 VERIFIED: NO

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyDefensin

Tax ID9785

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence