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MYP_019278
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Basic Information
Lumbricin I
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
62 amino acids
C330H497N89O95
Standard
Sequence
FSKYERQKDKRPYSERKNQYTGPQFLYPPERIPPQKVIKWNEEGLPIYEIPGEGGHAEPAAA
Physicochemical Analysis
7231.02 Da
8.20
0.86
0.58
0.0139
-1.30
0.50
-0.20
48.23
48.87
0.1290
12950.00
12950.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2963.58
-24.99
97.0
97.0
230.0
514.0
19.0
67.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0309957 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 15752
16 μg/mL
MIC
PaperLumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization.
RECORD: Rec_0316134 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 27325
12 μg/mL
MIC
PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
RECORD: Rec_0320779 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human erythrocytes
PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
RECORD: Rec_0335984 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas putida ATCC 17426
16 μg/mL
MIC
PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
RECORD: Rec_0344691 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
fungi C. albicons ATCC 10231
16 μg/mL
MIC
PaperLumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization.
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