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MYP_019278
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Basic Information
Lumbricin I
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
62 amino acids
C330H497N89O95
Standard
Sequence
FSKYERQKDKRPYSERKNQYTGPQFLYPPERIPPQKVIKWNEEGLPIYEIPGEGGHAEPAAA
Physicochemical Analysis
7231.02 Da
8.20
0.86
0.58
0.0139
-1.30
0.50
-0.20
48.23
48.87
0.1290
12950.00
12950.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2963.58
-24.99
97.0
97.0
230.0
514.0
19.0
67.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045357 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
No hemolytic activity against Human erythrocytes
Hemolysis
PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
RECORD: Rec_0054292 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Antimicrobial Peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperBiochim Biophys Acta. 1998 Oct 22;1408(1):67-76. | http://www.ncbi.nlm.nih.gov/pubmed/9784609 PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
RECORD: Rec_0067961 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
NOTE: Minimal inhibitory concentrations were determined by incubating approximately 104-105 CFU/ml of cells with serial dilutions of each peptide in a 96-well microtiter plate
PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
RECORD: Rec_0082075 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Serratia sp
PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
RECORD: Rec_0094179 VERIFIED: YES
Provenance & Taxonomy
Lumbricus rubellus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Streptococcus mutans ATCC 25175
30 μg/mL
MIC
PMID9784609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9784609/
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