Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC443H715N119O134S4

DescriptionStandard

        HVTAVELPSASIFLLPGSGIKLVIGNASLNIDMNWNVRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTSPMSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight9980.39 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.60

Charge Density (pH 7.0) 0.0207

GRAVY Index0.19

Hydrophobic Moment 0.54

Boman Index0.16

Instability Index25.81

Aliphatic Index 97.42

Aromaticity 0.0645

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4037.50

LogP -45.31

H-bond Donors 143.0

H-bond Acceptors 142.0

Rotatable Bonds 327.0

Heavy Atoms 700.0

Ring Count 14.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120257 VERIFIED: NO

Provenance & Taxonomy

OrganismDaphoenositta chrysoptera [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria