Peptide Database

Peptide NameHuman Prp (1-28)

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC146H233N37O34S4

DescriptionStandard

        MANLGCWMLVLFVATWSDLGLCKKRPKP
    

Molecular Weight3178.90 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)2.48

Net Charge (pH 7.4) 2.23

Charge Density (pH 7.0) 0.0885

GRAVY Index0.43

Hydrophobic Moment 0.25

Boman Index0.20

Instability Index41.42

Aliphatic Index 97.50

Aromaticity 0.1071

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1123.83

LogP -5.22

H-bond Donors 41.0

H-bond Acceptors 41.0

Rotatable Bonds 101.0

Heavy Atoms 221.0

Ring Count 7.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004069 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyProtein-derived CPP

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein/FITC labeling

C-TermAmidation

Other ModsN-term detail: Labelled with fluoresceine

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHuman bowes melanoma; N1e neuroblastoma; N2A cells

MethodFluorescence-based uptake assay

RECORD: Rec_0322486 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyHuman

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein/FITC labeling

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0412966 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein labeling

C-TermAmidation

Bio-Activity Profile

Function

Drug Delivery Vehicle Cell-penetrating peptide