Peptide Database

Peptide NameBrevinin-2TEb (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC129H221N39O38S4

DescriptionStandard

        GFMGDTLKGIARNAALALMNAAQCKLSGKC
    

Molecular Weight3054.63 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0913

GRAVY Index0.29

Hydrophobic Moment 0.63

Boman Index0.12

Instability Index-7.89

Aliphatic Index 85.00

Aromaticity 0.0333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1254.21

LogP -14.54

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 106.0

Heavy Atoms 210.0

Ring Count 1.0

Amide Bonds 32.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0409328 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana temporalis [Animal]; Indosylvirana temporalis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Hemolytic Anti-Gram-negative

TargetEscherichia coli

Activity0.04 μg/mL

MethodMIC

FIRST PREV 1 2 3

Showing 1 records on this page Ã‚Â· Page 3 of 3