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MYP_019242
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Basic Information
Brevinin-2TEb (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
30 amino acids
C129H221N39O38S4
Standard
Sequence
GFMGDTLKGIARNAALALMNAAQCKLSGKC
Physicochemical Analysis
3054.63 Da
9.39
2.74
2.50
0.0913
0.29
0.63
0.12
-7.89
85.00
0.0333
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1254.21
-14.54
45.0
45.0
106.0
210.0
1.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0252308 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
cholerae (PL 91)
60 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0292922 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent WO 2019/077634 A2 Evidence URLhttps://patents.google.com/patent/WO2019077634A2/en PatentWO 2019/077634 A2
RECORD: Rec_0310636 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa (ATCC 10145)
40 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0373109 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (ATCC25923)
40 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0395843 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
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