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MYP_019242
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Basic Information
Brevinin-2TEb (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
30 amino acids
C129H221N39O38S4
Standard
Sequence
GFMGDTLKGIARNAALALMNAAQCKLSGKC
Physicochemical Analysis
3054.63 Da
9.39
2.74
2.50
0.0913
0.29
0.63
0.12
-7.89
85.00
0.0333
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1254.21
-14.54
45.0
45.0
106.0
210.0
1.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010693 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli (NCLM 2064)
20 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0047220 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
24-30
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/D6N2U1/entry
RECORD: Rec_0080581 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]; Indosylvirana temporalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-positive
Staphylococcus aureus
0.04 μg/mL
MIC
RECORD: Rec_0116111 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus (NCLM 2156)
150 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0182910 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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