Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC264H393N67O85S4

DescriptionStandard

        MEKNFELKALEAINDLTDAELENVVGADKGQFDTISHECHWNTWQFLFTCCS
    

Molecular Weight5993.60 Da

Isoelectric Point (pI)4.31

Net Charge (pH 7.0)-7.34

Net Charge (pH 7.4) -7.71

Charge Density (pH 7.0) -0.1411

GRAVY Index-0.33

Hydrophobic Moment 0.58

Boman Index0.05

Instability Index5.72

Aliphatic Index 71.35

Aromaticity 0.1154

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2467.34

LogP -22.99

H-bond Donors 85.0

H-bond Acceptors 84.0

Rotatable Bonds 199.0

Heavy Atoms 420.0

Ring Count 10.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350803 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus sp. CH126_4D [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria