MYP_019204
Basic Information
[R10K]MVIIA (omega-conotoxin MVIIA analogue)
Miscellaneous
Standard
25 amino acids
C102H177N33O33S7
Standard
Sequence
CKGKGAKCSKLMYDCCTGSCRSGKC
Physicochemical Analysis
2618.15 Da
9.10
4.70
4.40
0.1878
-0.44
0.42
-0.21
48.43
19.60
0.0400
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1092.17
-16.35
46.0
45.0
92.0
175.0
1.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0432352 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin Ion channel blocker Calcium channel blocker N-type CaV2.2 inhibitor
rat CaV2.2 central α1B-d (α1B alone)
0.16±0.02 nM
Kd (two-electrode voltage-clamp kinetics in Xenopus oocytes)
RECORD: Rec_0432353 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin Ion channel blocker Calcium channel blocker N-type CaV2.2 inhibitor
rat CaV2.2 central α1B-d + β3
0.09±0.01 nM
Kd (two-electrode voltage-clamp kinetics in Xenopus oocytes)
RECORD: Rec_0432354 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin Ion channel blocker Calcium channel blocker N-type CaV2.2 inhibitor
rat CaV2.2 central α1B-d + β3 + α2δ
8.9±2.2 nM
Kd (two-electrode voltage-clamp kinetics in Xenopus oocytes)
Showing 3 records · Page 2 of 2