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MYP_019184
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Basic Information
Bombinin-like peptide 7
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C114H191N33O33
Standard
Sequence
GIGGALLSAGKSALKGLAKGLAEHFAN
Physicochemical Analysis
2551.94 Da
9.70
1.85
1.59
0.0684
0.41
0.60
0.28
-11.30
108.89
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1047.51
-11.49
36.0
36.0
88.0
180.0
2.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0214128 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
256 μg/mL
Hemolysis
PMID28636781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28636781/
RECORD: Rec_0236639 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 40.7%, E 0.0%, T 44.4%, C 14.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0261236 VERIFIED: YES
Provenance & Taxonomy
Oriental fire-bellied toad [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Micrococcus luteus, and S. cerevisae Ke T et al., 2012. ALso has anticancer effects on human hepatic adenocarcinoma SK-HEP-1 cells
0.99 μM
IC50
PaperSequence of a gene from Bombina orientalis coding for the antimicrobial peptide BLP-7.
RECORD: Rec_0294528 VERIFIED: NO
Provenance & Taxonomy
Bombina variegata [Animal] [Animal]; Bombina orientalis [Animal] [Animal]; Bombina maxima [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0299287 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
16 μg/mL
MIC
PMID28636781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28636781/
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