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MYP_019180
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Basic Information
Vcn-23
Antimicrobial
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
23 amino acids
C139H242N36O25S
Standard
Sequence
FFKKVKKSVKKRLKKIFKKPMVI
Physicochemical Analysis
2849.70 Da
11.56
10.75
10.53
0.4674
-0.44
0.79
-0.27
-9.47
88.70
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1037.06
-2.30
37.0
37.0
107.0
201.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081300 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E. casseliflavus ATCC 700327
0.70 μM
MIC
PaperAquiluscidin, a Cathelicidin from Crotalus aquilus, and the Vcn-23 Derivative Peptide, Have Anti-Microbial Activity against Gram-Negative and Gram-Positive Bacteria
RECORD: Rec_0120526 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 6538 or clinical strain
1.40 μM
MIC
PaperAquiluscidin, a Cathelicidin from Crotalus aquilus, and the Vcn-23 Derivative Peptide, Have Anti-Microbial Activity against Gram-Negative and Gram-Positive Bacteria
RECORD: Rec_0151051 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
rat RBC: less than 2% hemolysis at 50 uM. HEK293 cells
~60 μM
IC50
PaperAquiluscidin, a Cathelicidin from Crotalus aquilus, and the Vcn-23 Derivative Peptide, Have Anti-Microbial Activity against Gram-Negative and Gram-Positive Bacteria
RECORD: Rec_0177327 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa or clinical strain
1.40 μM
MIC
PaperAquiluscidin, a Cathelicidin from Crotalus aquilus, and the Vcn-23 Derivative Peptide, Have Anti-Microbial Activity against Gram-Negative and Gram-Positive Bacteria
RECORD: Rec_0300116 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. typhymurium ATCC 14028
0.70 μM
MIC
PaperAquiluscidin, a Cathelicidin from Crotalus aquilus, and the Vcn-23 Derivative Peptide, Have Anti-Microbial Activity against Gram-Negative and Gram-Positive Bacteria
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