Peptide Database

Peptide NameBovine Beta-defensin 11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC136H241N45O36S5

DescriptionStandard

        PLSCGRNKGICVPIRCPGKMKQIGTCVGRAV
    

Molecular Weight3242.97 Da

Isoelectric Point (pI)9.95

Net Charge (pH 7.0)5.92

Net Charge (pH 7.4) 5.80

Charge Density (pH 7.0) 0.1908

GRAVY Index0.10

Hydrophobic Moment 0.66

Boman Index-0.01

Instability Index43.82

Aliphatic Index 81.61

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1295.15

LogP -15.13

H-bond Donors 50.0

H-bond Acceptors 47.0

Rotatable Bonds 108.0

Heavy Atoms 222.0

Ring Count 3.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404132 VERIFIED: YES

Provenance & Taxonomy

OrganismBos grunniens [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)