Peptide Database

Peptide NameCorticostatin-4 (Corticostatin IV; Macrophage antibiotic peptide MCP-2; lagomorphs, mammals, anim

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiviral

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC161H282N62O36S6

DescriptionStandard

        VVCACRRALCLPLERRAGFCRIRGRIHPLCCRR
    

Molecular Weight3854.75 Da

Isoelectric Point (pI)11.12

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.41

Charge Density (pH 7.0) 0.2353

GRAVY Index0.14

Hydrophobic Moment 0.46

Boman Index-0.27

Instability Index87.05

Aliphatic Index 97.58

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1600.02

LogP -15.14

H-bond Donors 67.0

H-bond Acceptors 51.0

Rotatable Bonds 126.0

Heavy Atoms 265.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0432337 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideThree disulfide bridges

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStreptococcus agalactiae Type I-A

Methodbactericidal assay

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