MYP_019136
Basic Information
Corticostatin-4 (Corticostatin IV; Macrophage antibiotic peptide MCP-2; lagomorphs, mammals, anim
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antiviral
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Venom / Toxin General toxin Toxic
Standard
33 amino acids
C161H282N62O36S6
Standard
Sequence
VVCACRRALCLPLERRAGFCRIRGRIHPLCCRR
Physicochemical Analysis
3854.75 Da
11.12
7.76
7.41
0.2353
0.14
0.46
-0.27
87.05
97.58
0.0303
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1600.02
-15.14
67.0
51.0
126.0
265.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0320516 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Toxic Hemolytic Anti-Gram-positive Anti-Gram-negative
RECORD: Rec_0339975 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μg/mL
Hemolysis
RECORD: Rec_0373793 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Virus]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bridges
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Staphylococcus aureus strains 566, 502A, J.F. (reduction 2.4->4.1 logs), Staphylococcus epidermidis UCLA-622 (reduction >4.1 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A
Showing 3 records on this page · Page 2 of 2