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MYP_019136
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Basic Information
Corticostatin-4 (Corticostatin IV; Macrophage antibiotic peptide MCP-2; lagomorphs, mammals, anim
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
33 amino acids
C161H282N62O36S6
Standard
Sequence
VVCACRRALCLPLERRAGFCRIRGRIHPLCCRR
Physicochemical Analysis
3854.75 Da
11.12
7.76
7.41
0.2353
0.14
0.46
-0.27
87.05
97.58
0.0303
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1600.02
-15.14
67.0
51.0
126.0
265.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006313 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral
PaperPubMed PMID: 6643497 | PubMed PMID: 3988726 | PubMed PMID: 1311240 PMID6643497;3988726;1311240 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6643497/
RECORD: Rec_0062046 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
9986
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-31; 5-20; 10-30
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
RECORD: Rec_0068671 VERIFIED: YES
Provenance & Taxonomy
Mammalia [Animal]
Defensin
40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-20; 5-30; 10-31
Bio-Activity Profile
Antimicrobial
PMID3988726 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3988726/
RECORD: Rec_0101472 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Defensin
9986
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
PMID2745983 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2745983/
RECORD: Rec_0166714 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20050260715A1/en PatentUS 2005/0260715 A1
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