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MYP_019135
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Basic Information
Ceratotoxin-C (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
32 amino acids
C142H255N37O35
Standard
Sequence
SLGGVISGAKKVAKVAIPIGKAVLPVVAKLVG
Physicochemical Analysis
3040.77 Da
10.60
4.46
4.24
0.1392
1.16
0.59
0.40
8.76
152.19
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1118.40
-7.81
38.0
40.0
102.0
214.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0208265 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli LE 392
5.0 μM
MIC
PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0245307 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
cloacae 13047
5 μM
MIC
PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0248815 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis 6633
5.9 μM
MIC
PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0262717 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae 13047
50.0 μM
MIC
PMID9569644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9569644/
RECORD: Rec_0275019 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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